reversible/irreversible

aluminium may be

due

to

formation

of

aluminium complex. Aluminium

has

high

affinity

for

proteins,

carbohydrates and polynucleotides and may exist as reversible

macromolecular

complex

of

cation/polyanion

[5].

If

the

cation/polyanion ratio exceeds a threshold value, irreversible

complex

can

be

formed

giving

rise

to

inhibitory

effect

of

and

of

aluminium. Polynuclear ions

can

produce

Though

membrane

changes

aggregate

biomolecules

[4].

the

formation

reversible/irreversible

complex

can

be

postulated

to

explain

biphasic effect of aluminium, it remains to be elucidated in

detail.